Parents

• Richard Penn Smith (1799–1854)
• Isabella Stratton Knisell (1812–1880)

Spouses

• Elizabeth Beebe Melville (1841–?)

Siblings

• Richard Penn "Colonel" Smith Jr. (1837–?)
• Isabella Penn Smith (1839–?)
• Eliza Arnold Smith (1841–?)
• Maria Lewis Smith (1844–1869)

Children

• William Moore Smith Jr. (1867–1877)
• Isabella Knisell Smith (1868–?)
• Edna Gould Smith (1874–?)

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