Parents

• Mason Loch "Parson" Weems (1759–1825)
• Frances Ewell (Fanny) (1775–1843)

Spouses

• Nancy Otis Rickard

Siblings

• Frances Ewell Weems (1796–1813)
• Susan Ann Weems (1798–1821)
• Charlotte Ewell Weems (1801–1843)
• Nancy Ewell (Ann) Weems (1802–1833)
• Harriet Ewell Weems (1804–?)
• Mason Locke Weems Dr. II (1806–1856)
• Marion Weems d.inf (1808–1809)
• Francis Marion Weems Dr. (1809–1865)
• Milton Weems d.inf (1812–1813)

Children

• Mary ?Griselda? Weems
• Frances Anne Weems (1825–1846)
• Jesse Ewell Weems Jr.

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